The Dresden-Klotzsche Airport, located north of the city, has flight connections to the majority of important German cities, as well as a few European destinations. Thus, there is a possibility of international transfers. The airport can be reached by bus (lines 77 and 97), tram line (line 7, change for the bus at tram station Infineon Nord), and local train (S-Bahn line 22), the latter taking 21 minutes.
Dresden Neustadt and Dresden Hauptbanhof are the two largest train stations, situated on the northern and southern side of the Elbe respectively. Dresden Neustadt is just north of the New Town and offers good train connections, some terminating there and not at the main train station (Hauptbanhof). It is easily accessible by tram or car. Dresden Hauptbanhof is located by Dresden's main shopping street, Prager Straße, and is thus in a short walking distance from most central attractions in Old Town. It has the most well-connected train service in Dresden (thus serving as the main station), and can be reached by bus and tram, as well as by car.
Dresden has good bus connections, with BerlinLinienbus operating eight buses from Berlin to Dresden daily (most connecting to the Hauptbanhof station, but also other bus stations such as Schlesischer Platz and Neustadt station), and Mein Fern Bus also connecting Dresden with Berlin and other destinations. Dresden is also easily accessed by car through the German highway system and the new Autobahn leading to Prague, which has just recently been finished.
Residence permits are issued in two steps both for free-lance/self-employed individuals and also those with salaried employment.
A residence permit for foreign employees who are not citizens of the EU, the EEA or Switzerland can be issued in the following forms:
The application for a residence permit must be filed at the immigration office of the regional capital of Dresden no later than the expiry date of the entry visa. Here you must go to the Central Passport and Registration Office, Theaterstraße 11, 01067 Dresden.
The following requirements must be fulfilled:
Residence for the purpose of employment includes:
Employment
This term applies to salaried employment in particular when there is an employment contract. The term employment' also covers professional training and further training.
Self-employed/free-lance activities
Individuals who would like to be independently employed in Germany can also obtain a residence permit with a three-year limit. If the individual or company can prove that business has gone well during this period, a permanent residence permit can be issued.
A permanent residence permit is issued to consolidate the residence of a foreigner on German territory and is for an unlimited period. Furthermore, it authorizes him or her to perform both regular employment and self-employment or free-lance activities. The basic requirements for the issue of a permanent residence permit are five year possession of a residence permit, reliable means of support, proof of payment of the required contributions to the statutory pension insurance for at least 60 months, lack of a criminal record, work permit, possession of the required knowledge for employment, sufficient knowledge of the German language, basic knowledge of legal and social regulations and of living conditions in Germany, sufficient living space.
Besides the basic regulations of the residence law for issuing a permanent residence permit, there are also several special regulations which also (under extenuating circumstances) govern the issue of permanent residence permits:
Information taken from: http://welcome.dresden.de/en/entry/permit.php
More information can be found at the link